Enhanced production of recombinant proteins with Corynebacterium glutamicum by deletion of insertion sequences (IS elements)

BACKGROUND: In most bacteria, various jumping genetic elements including insertion sequences elements (IS elements) cause a variety of genetic rearrangements resulting in harmful effects such as genome and recombinant plasmid instability. The genetic stability of a plasmid in a host is critical for...

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Publicado en:Microb Cell Fact
Autores principales: Choi, Jae Woong, Yim, Sung Sun, Kim, Min Jeong, Jeong, Ki Jun
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696348/
https://ncbi.nlm.nih.gov/pubmed/26715464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-015-0401-7
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