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Ablation of Dicer leads to widespread perturbation of signaling pathways

Dicer is an essential ribonuclease involved in the biogenesis of miRNAs. Previous studies have reported downregulation of Dicer in multiple cancers including hepatocellular carcinoma. To identify signaling pathways that are altered upon Dicer depletion, we carried out quantitative phosphotyrosine pr...

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Detalhes bibliográficos
Publicado no:Biochem Biophys Res Commun
Main Authors: Sahasrabuddhe, Nandini A., Huang, Tai-Chung, Kumar, Praveen, Yang, Yi, Ghosh, Bidyut, Leach, Steven D., Chaerkady, Raghothama, Pandey, Akhilesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696065/
https://ncbi.nlm.nih.gov/pubmed/26032504
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.05.077
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