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Androgen pathway resistance in prostate cancer and therapeutic implications

INTRODUCTION: Metastatic prostate cancer is an incurable disease that is treated with a variety of hormonal therapies targeting various nodes of the androgen receptor (AR) pathway. Invariably patients develop resistance and become castration resistant. Common treatments for castration-resistant dise...

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Bibliografiske detaljer
Udgivet i:Expert Opin Pharmacother
Main Authors: Maughan, Benjamin L, Antonarakis, Emmanuel S
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4696015/
https://ncbi.nlm.nih.gov/pubmed/26067250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14656566.2015.1055249
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