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Mitochondrial leukoencephalopathy and complex II deficiency associated with a recessive SDHB mutation with reduced penetrance

Mitochondrial disease involving complex II is rare among respiratory chain deficiencies and its genetic cause remains often unknown. Two main clinical presentations are associated with this biochemical defect: mitochondrial encephalomyopathy and susceptibility to tumors. Only one homozygous SDHB mut...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab Rep
Main Authors: Ardissone, Anna, Invernizzi, Federica, Nasca, Alessia, Moroni, Isabella, Farina, Laura, Ghezzi, Daniele
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695914/
https://ncbi.nlm.nih.gov/pubmed/26925370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgmr.2015.10.006
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