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Clinical Implications of Hedgehog Pathway Signaling in Prostate Cancer
Activity in the Hedgehog pathway, which regulates GLI-mediated transcription, is important in organogenesis and stem cell regulation in self-renewing organs, but is pathologically elevated in many human malignancies. Mutations leading to constitutive activation of the pathway have been implicated in...
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| 出版年: | Cancers (Basel) |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
MDPI
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695871/ https://ncbi.nlm.nih.gov/pubmed/26426053 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7040871 |
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