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p16 gene methylation in colorectal cancers associated with Duke′s staging

AIM: To explore the association of methylation of the CpG island in the promotor of the P16 tumor suppressor gene with the clinicopathological characteristics of the colorectal cancers. METHODS: Methylation-specific PCR (MSP) was used to detect P16 methylation of 62 sporadic colorectal cancer specim...

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Detalhes bibliográficos
Publicado no:World J Gastroenterol
Main Authors: Yi, Jing, Wang, Zhi-Wei, Cang, Hui, Chen, Yu-Ying, Zhao, Ren, Yu, Bao-Ming, Tang, Xue-Ming
Formato: Artigo
Idioma:Inglês
Publicado em: Baishideng Publishing Group Inc 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695583/
https://ncbi.nlm.nih.gov/pubmed/11819863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v7.i5.722
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