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A Small n Sequential Multiple Assignment Randomized Trial Design For Use in Rare Disease Research
BACKGROUND: Clinical trials in rare diseases are difficult to conduct due to the limited number of patients available with each disorder. We developed a Phase 2 trial which is a small n sequential multiple assignment randomized trial (snSMART) design to test several treatments for a rare disease for...
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Publicado no: | Contemp Clin Trials |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695231/ https://ncbi.nlm.nih.gov/pubmed/26586608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cct.2015.11.010 |
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