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Time-course gene profiling and networks in demethylated retinoblastoma cell line

Retinoblastoma, a very aggressive cancer of the developing retina, initiatiates by the biallelic loss of RB1 gene, and progresses very quickly following RB1 inactivation. While its genome is stable, multiple pathways are deregulated, also epigenetically. After reviewing the main findings in relation...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Malusa, Federico, Taranta, Monia, Zaki, Nazar, Cinti, Caterina, Capobianco, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695145/
https://ncbi.nlm.nih.gov/pubmed/26143641
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