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Centrosome aberrations in human mammary epithelial cells driven by cooperative interactions between p16(INK4a) deficiency and telomere-dependent genotoxic stress
Virtually all human cancers display chromosome instability (CIN), a condition in which chromosomes are gained or lost at a high rate. CIN occurs early in cancer development where it may undermine the advance of the neoplastic disease. With the aim of establishing the mechanisms underlying CIN in can...
Tallennettuna:
Julkaisussa: | Oncotarget |
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Päätekijät: | , , , , , , |
Aineistotyyppi: | Artigo |
Kieli: | Inglês |
Julkaistu: |
Impact Journals LLC
2015
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Aiheet: | |
Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4695057/ https://ncbi.nlm.nih.gov/pubmed/26318587 |
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