RUNX2 and TAZ-dependent signaling pathways regulate soluble E-Cadherin levels and tumorsphere formation in breast cancer cells

Intratumoral heterogeneity and treatment resistance drive breast cancer (BC) metastasis and recurrence. The RUNX2 transcription factor is upregulated in early stage luminal BC. However, the precise mechanism by which RUNX2 regulates an oncogenic phenotype in luminal BCs remains an enigma. We show th...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Brusgard, Jessica L., Choe, Moran, Chumsri, Saranya, Renoud, Keli, MacKerell, Alexander D., Sudol, Marius, Passaniti, Antonino
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2015
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4695049/
https://ncbi.nlm.nih.gov/pubmed/26320173
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