Genome-wide analysis of DNA methylation and gene expression patterns in purified, uncultured human liver cells and activated hepatic stellate cells

BACKGROUND & AIMS: Liver fibrogenesis – scarring of the liver that can lead to cirrhosis and liver cancer – is characterized by hepatocyte impairment, capillarization of liver sinusoidal endothelial cells (LSECs) and hepatic stellate cell (HSC) activation. To date, the molecular determinants of...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: El Taghdouini, Adil, Sørensen, Anita L., Reiner, Andrew H., Coll, Mar, Verhulst, Stefaan, Mannaerts, Inge, Øie, Cristina I., Smedsrød, Bård, Najimi, Mustapha, Sokal, Etienne, Luttun, Aernout, Sancho-Bru, Pau, Collas, Philippe, van Grunsven, Leo A.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper: Pathology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694948/
https://ncbi.nlm.nih.gov/pubmed/26353929
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