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Tumor suppressor NDRG2 inhibits glycolysis and glutaminolysis in colorectal cancer cells by repressing c-Myc expression

Cancer cells use glucose and glutamine as the major sources of energy and precursor intermediates, and enhanced glycolysis and glutamimolysis are the major hallmarks of metabolic reprogramming in cancer. Oncogene activation and tumor suppressor gene inactivation alter multiple intracellular signalin...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Xu, Xinyuan, Li, Jianying, Sun, Xiang, Guo, Yan, Chu, Dake, Wei, Li, Li, Xia, Yang, Guodong, Liu, Xinping, Yao, Libo, Zhang, Jian, Shen, Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694893/
https://ncbi.nlm.nih.gov/pubmed/26317652
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