Disruption and inactivation of the PP2A complex promotes the proliferation and angiogenesis of hemangioma endothelial cells through activating AKT and ERK

Hemangioma is a benign vascular neoplasm of unknown etiology. In this study, we generated an endothelial-specific PyMT gene-expressing transgenic mouse model that spontaneously develops hemangioma. Based on this transgenic model, a specific binding between PyMT and the core AC dimer of protein phosp...

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Foilsithe in:Oncotarget
Main Authors: Xie, Furong, Bao, Xin, Yu, Jingshuang, Chen, Wantao, Wang, Lizhen, Zhang, Zhiyuan, Xu, Qin
Formáid: Artigo
Teanga:Inglês
Foilsithe: Impact Journals LLC 2015
Ábhair:
Research Paper
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694857/
https://ncbi.nlm.nih.gov/pubmed/26308070
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