The Schistosoma mansoni Cytochrome P450 (CYP3050A1) Is Essential for Worm Survival and Egg Development

Schistosomiasis affects millions of people in developing countries and is responsible for more than 200,000 deaths annually. Because of toxicity and limited spectrum of activity of alternatives, there is effectively only one drug, praziquantel, available for its treatment. Recent data suggest that d...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Ziniel, Peter D., Karumudi, Bhargava, Barnard, Andrew H., Fisher, Ethan M. S., Thatcher, Gregory R. J., Podust, Larissa M., Williams, David L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694641/
https://ncbi.nlm.nih.gov/pubmed/26713732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004279
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