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Downregulation of cell cycle-related proteins in ovarian cancer line and cell cycle arrest induced by microRNA

Objective: The effect of miR-449 and miR-34 on the growth, cell cycle and target gene expressions of ovarian cancer cell line SKOV3 and SKOV3-ipl was discussed. Method: Real-time quantitative reverse transcription PCR was employed to detect the expressions of miR-449a/b and miR-34b, c in SKOV3 and S...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Yuan, Jian-Mei, Shi, Xue-Jun, Sun, Ping, Liu, Jun-Xia, Wang, Wei, Li, Ming, Ling, Feng-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694355/
https://ncbi.nlm.nih.gov/pubmed/26770455
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