Screening of a kinase library reveals novel pro-senescence kinases and their common NF-κB-dependent transcriptional program

Cellular senescence results in proliferation arrest and acquisition of hallmarks such as the Senescence-Associated Secretory Phenotype (SASP). Senescence is involved in regulating numerous physio-pathological responses, including embryonic development, cancer, and several aging-related diseases. Onl...

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Veröffentlicht in:Aging (Albany NY)
Hauptverfasser: Ferrand, Mylène, Kirsh, Olivier, Griveau, Audrey, Vindrieux, David, Martin, Nadine, Defossez, Pierre-Antoine, Bernard, David
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694068/
https://ncbi.nlm.nih.gov/pubmed/26583757
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