OTX2 regulates the expression of TAp63 leading to macular and cochlear neuroepithelium development

OTX proteins, homologs of the Drosophila orthodenticle (Otd), are important for the morphogenesis of the neuroectoderm, and for the central nervous system formation. OTX1 and OTX2 are important for the cochlea and macula development, indeed when OTX1 is knocked down, these organs undergo development...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Palombo, Ramona, Porta, Giovanni, Bruno, Ernesto, Provero, Paolo, Serra, Valeria, Neduri, Karthik, Viziano, Andrea, Alessandrini, Marco, Micarelli, Alessandro, Ottaviani, Fabrizio, Melino, Gerry, Terrinoni, Alessandro
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694063/
https://ncbi.nlm.nih.gov/pubmed/26554466
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