Pseudomonas aeruginosa Triggers Macrophage Autophagy To Escape Intracellular Killing by Activation of the NLRP3 Inflammasome

Assembly of the inflammasome has recently been identified to be a critical event in the initiation of inflammation. However, its role in bacterial killing remains unclear. Our study demonstrates that Pseudomonas aeruginosa infection induces the assembly of the NLRP3 inflammasome and the sequential s...

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Bibliographic Details
Published in:Infect Immun
Main Authors: Deng, Qiuchan, Wang, Yi, Zhang, Yuanqing, Li, Meiyu, Li, Dandan, Huang, Xi, Wu, Yongjian, Pu, Jieying, Wu, Minhao
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Bacterial Infections
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4694000/
https://ncbi.nlm.nih.gov/pubmed/26467446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00945-15
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