Hyper‐responsive Toll‐like receptor 7 and 9 activation in NADPH oxidase‐deficient B lymphoblasts

Chronic granulomatous disease (CGD) is an inherited immunodeficiency linked with mutations in the multi‐subunit leucocyte NADPH oxidase. Myeloid‐derived phagocytic cells deficient in NADPH oxidase fail to produce sufficient levels of reactive oxygen species to clear engulfed pathogens. In this study...

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Bibliographic Details
Published in:Immunology
Main Authors: McLetchie, Shawna, Volpp, Bryan D., Dinauer, Mary C., Blum, Janice S.
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693894/
https://ncbi.nlm.nih.gov/pubmed/26340429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12530
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