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Malignant Brain Tumor Repeats: A Three-Leaved Propeller Architecture with Ligand/Peptide Binding Pockets

We report on the X-ray structure of three 100-amino acid mbt repeats in h-l(3)mbt, a polycomb group protein involved in transcriptional repression, whose gene is located in a region of chromosome 20 associated with hematopoietic malignancies. Interdigitation between the extended arms and cores of th...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Wang, Wooi Koon, Tereshko, Valentina, Boccuni, Piernicola, MacGrogan, Donal, Nimer, Stephen D., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693639/
https://ncbi.nlm.nih.gov/pubmed/12842041
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