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Waxing and waning of MET amplification in EGFR mutated NSCLC in response to presence and absence of erlotinib selection pressure

Somatic sensitizing mutations in the epidermal growth factor receptor (EGFR) are associated with response to EGFR tyrosine kinase inhibitors (TKIs), however acquired resistance and subsequent progression of disease inevitably occurs. One such mechanism of acquired resistance (AR), a second site muta...

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Detalles Bibliográficos
Publicado en:J Thorac Oncol
Main Authors: Womack, Joel P., Varella-Garcia, Marileila, Camidge, D. Ross
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693630/
https://ncbi.nlm.nih.gov/pubmed/26709484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0000000000000642
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