β‐Guanidinopropionic acid extends the lifespan of Drosophila melanogaster via an AMP‐activated protein kinase‐dependent increase in autophagy

Previous studies have demonstrated that AMP‐activated protein kinase (AMPK) controls autophagy through the mammalian target of rapamycin (mTOR) and Unc‐51 like kinase 1 (ULK1/Atg1) signaling, which augments the quality of cellular housekeeping, and that β‐guanidinopropionic acid (β‐GPA), a creatine...

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Detalhes bibliográficos
Publicado no:Aging Cell
Main Authors: Yang, Si, Long, Li‐Hong, Li, Di, Zhang, Jian‐Kang, Jin, Shan, Wang, Fang, Chen, Jian‐Guo
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693457/
https://ncbi.nlm.nih.gov/pubmed/26120775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12371
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