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A Novel Aspect of Tumorigenesis—BMI1 Functions in Regulating DNA Damage Response
BMI1 plays critical roles in maintaining the self-renewal of hematopoietic, neural, intestinal stem cells, and cancer stem cells (CSCs) for a variety of cancer types. BMI1 promotes cell proliferative life span and epithelial to mesenchymal transition (EMT). Upregulation of BMI1 occurs in multiple ca...
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| Publicat a: | Biomolecules |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
MDPI
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4693283/ https://ncbi.nlm.nih.gov/pubmed/26633535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biom5043396 |
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