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Increasing the Time Interval between PCV Chemotherapy Cycles as a Strategy to Improve Duration of Response in Low-Grade Gliomas: Results from a Model-Based Clinical Trial Simulation

Background. We previously developed a mathematical model capturing tumor size dynamics of adult low-grade gliomas (LGGs) before and after treatment either with PCV (Procarbazine, CCNU, and Vincristine) chemotherapy alone or with radiotherapy (RT) alone. Objective. The aim of the present study was to...

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Veröffentlicht in:Comput Math Methods Med
Hauptverfasser: Mazzocco, Pauline, Honnorat, Jérôme, Ducray, François, Ribba, Benjamin
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi Publishing Corporation 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4693002/
https://ncbi.nlm.nih.gov/pubmed/26788118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/297903
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