Kinematics and thermodynamics of a folding heteropolymer.
In order to elucidate the folding dynamics of protein, we have carried out numerical simulations of a heteropolymer model of self-interacting random chains. We find that folding propensity depends strongly on sequence and that both folding and nonfolding sequences exist. Furthermore we show that fol...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1993
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC46929/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8327518/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.13.6365 |
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