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How can polygenic inheritance be used in population screening for common diseases?
Advances in genomics have near-term impact on diagnosis and management of monogenic disorders. For common complex diseases, the use of genomic information from multiple loci (polygenic model) is generally not useful for diagnosis and individual prediction. In principle, the polygenic model could be...
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| Publicado en: | Genet Med |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692802/ https://ncbi.nlm.nih.gov/pubmed/23412608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2012.182 |
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