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How can polygenic inheritance be used in population screening for common diseases?
Advances in genomics have near-term impact on diagnosis and management of monogenic disorders. For common complex diseases, the use of genomic information from multiple loci (polygenic model) is generally not useful for diagnosis and individual prediction. In principle, the polygenic model could be...
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| Veröffentlicht in: | Genet Med |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4692802/ https://ncbi.nlm.nih.gov/pubmed/23412608 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gim.2012.182 |
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