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Orthotopic Implantation and Peripheral Immune Cell Monitoring in the II-45 Syngeneic Rat Mesothelioma Model

The enormous upsurge of interest in immune-based treatments for cancer such as vaccines and immune checkpoint inhibitors, and increased understanding of the role of the tumor microenvironment in treatment response, collectively point to the need for immune-competent orthotopic models for pre-clinica...

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Publicado en:J Vis Exp
Main Authors: Weir, Chris J., Hudson, Amanda L., Peters, Lyndsay, Howell, Viive M.
Formato: Artigo
Idioma:Inglês
Publicado: MyJove Corporation 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692642/
https://ncbi.nlm.nih.gov/pubmed/26485154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/53019
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