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Eye Irritation Test (EIT) for Hazard Identification of Eye Irritating Chemicals using Reconstructed Human Cornea-like Epithelial (RhCE) Tissue Model

To comply with the Seventh Amendment to the EU Cosmetics Directive and EU REACH legislation, validated non-animal alternative methods for reliable and accurate assessment of ocular toxicity in man are needed. To address this need, we have developed an eye irritation test (EIT) which utilizes a three...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Kaluzhny, Yulia, Kandárová, Helena, d’Argembeau-Thornton, Laurence, Kearney, Paul, Klausner, Mitchell
Формат: Artigo
Язык:Inglês
Опубликовано: MyJove Corporation 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692559/
https://ncbi.nlm.nih.gov/pubmed/26325674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52979
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