A Randomized Trial of Pharmacogenetic Warfarin Dosing in Naïve Patients with Non-Valvular Atrial Fibrillation

Genotype-guided warfarin dosing have been proposed to improve patient’s management. This study is aimed to determine whether a CYP2C9- VKORC1- CYP4F2-based pharmacogenetic algorithm is superior to a standard, clinically adopted, pharmacodynamic method. Two-hundred naïve patients with non-valvular at...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Pengo, Vittorio, Zambon, Carlo-Federico, Fogar, Paola, Padoan, Andrea, Nante, Giovanni, Pelloso, Michela, Moz, Stefania, Frigo, Anna Chiara, Groppa, Francesca, Bozzato, Dania, Tiso, Enrico, Gnatta, Elisa, Denas, Gentian, Padayattil Jose, Seena, Padrini, Roberto, Basso, Daniela, Plebani, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692529/
https://ncbi.nlm.nih.gov/pubmed/26710337
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145318
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