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Full trans–activation mediated by the immediate–early protein of equine herpesvirus 1 requires a consensus TATA box, but not its cognate binding sequence

The immediate-early protein (IEP) of equine herpesvirus 1 (EHV-1) has extensive homology to the IEP of alphaherpesviruses and possesses domains essential for trans-activation, including an acidic trans-activation domain (TAD) and binding domains for DNA, TFIIB, and TBP. Our data showed that the IEP...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Kim, Seong K., Shakya, Akhalesh K., O'Callaghan, Dennis J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692279/
https://ncbi.nlm.nih.gov/pubmed/26541315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2015.10.026
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