Hepatocyte Nuclear Factor 4α Controls Iron Metabolism and Regulates Transferrin Receptor 2 in Mouse Liver

Iron is an essential element in biological systems, but excess iron promotes the formation of reactive oxygen species, resulting in cellular toxicity. Several iron-related genes are highly expressed in the liver, a tissue in which hepatocyte nuclear factor 4α (HNF4α) plays a critical role in control...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Matsuo, Shunsuke, Ogawa, Masayuki, Muckenthaler, Martina U., Mizui, Yumiko, Sasaki, Shota, Fujimura, Takafumi, Takizawa, Masayuki, Ariga, Nagayuki, Ozaki, Hiroaki, Sakaguchi, Masakiyo, Gonzalez, Frank J., Inoue, Yusuke
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Gene Regulation
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692214/
https://ncbi.nlm.nih.gov/pubmed/26527688
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.694414
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