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Perspective on Adeno-Associated Virus Capsid Modification for Duchenne Muscular Dystrophy Gene Therapy

Duchenne muscular dystrophy (DMD) is a X-linked, progressive childhood myopathy caused by mutations in the dystrophin gene, one of the largest genes in the genome. It is characterized by skeletal and cardiac muscle degeneration and dysfunction leading to cardiac and/or respiratory failure. Adeno-ass...

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Detalhes bibliográficos
Publicado no:Hum Gene Ther
Main Authors: Nance, Michael E., Duan, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692109/
https://ncbi.nlm.nih.gov/pubmed/26414293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2015.107
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