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Genome management and mismanagement—cell-level opportunities and challenges of whole-genome duplication

Whole-genome duplication (WGD) doubles the DNA content in the nucleus and leads to polyploidy. In whole-organism polyploids, WGD has been implicated in adaptability and the evolution of increased genome complexity, but polyploidy can also arise in somatic cells of otherwise diploid plants and animal...

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Bibliographic Details
Published in:Genes Dev
Main Authors: Yant, Levi, Bomblies, Kirsten
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691946/
https://ncbi.nlm.nih.gov/pubmed/26637526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.271072.115
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