PHD Finger Recognition of Unmodified Histone H3R2 Links UHRF1 to Regulation of Euchromatic Gene Expression

Histone methylation occurs on both lysine and arginine residues, and its dynamic regulation plays a critical role in chromatin biology. Here we identify the UHRF1 PHD finger (PHD(UHRF1)), an important regulator of DNA CpG methylation, as a histone H3 unmodified arginine 2 (H3R2) recognition modality...

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Udgivet i:Mol Cell
Main Authors: Rajakumara, Eerappa, Wang, Zhentian, Ma, Honghui, Hu, Lulu, Chen, Hao, Lin, Yan, Guo, Rui, Wu, Feizhen, Li, Haitao, Lan, Fei, Shi, Yujiang Geno, Xu, Yanhui, Patel, Dinshaw J., Shi, Yang
Format: Artigo
Sprog:Inglês
Udgivet: 2011
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691841/
https://ncbi.nlm.nih.gov/pubmed/21777816
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.07.006
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