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Sustained dual drug delivery of anti-inhibitory molecules for treatment of spinal cord injury

Myelin-associated inhibitors (MAIs) and chondroitin sulfate proteoglycans (CSPGs) are major contributors to axon growth inhibition following spinal cord injury and limit functional recovery. The NEP1-40 peptide competitively binds the Nogo receptor and partially blocks inhibition from MAIs, while ch...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Wilems, Thomas S., Sakiyama-Elbert, Shelly E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691576/
https://ncbi.nlm.nih.gov/pubmed/26122130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.06.031
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