Dormant Intestinal Stem Cells are Regulated by PTEN and Nutritional Status

The cellular and molecular mechanisms underlying adaptive changes to physiological stress within the intestinal epithelium remain poorly understood. Here, we show that PTEN, a negative regulator of the PI3K→AKT→mTORC1 signaling pathway, is an important regulator of dormant intestinal stem cells (dIS...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:Cell Rep
Glavni autori: Richmond, Camilla A., Shah, Manasvi S., Deary, Luke T., Trotier, Danny C., Thomas, Horatio, Ambruzs, Dana M., Jiang, Lijie, Whiles, Bristol B., Rickner, Hannah D., Montgomery, Robert K., Tovaglieri, Alessio, Carlone, Diana L., Breault, David T.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691543/
https://ncbi.nlm.nih.gov/pubmed/26686631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.11.035
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items