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Mitogen-regulated Ca2+ current of T lymphocytes is activated by depletion of intracellular Ca2+ stores.

Stimulated influx of Ca2+ across the plasma membrane of T lymphocytes is an essential triggering signal for T-cell activation by antigen. Regulation of the T-cell Ca2+ conductance is not understood; conflicting evidence supports direct activation by inositol 1,4,5-trisphosphate (IP3) or by a signal...

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Bibliografski detalji
Glavni autori: Zweifach, A, Lewis, R S
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC46915/
https://ncbi.nlm.nih.gov/pubmed/8392195
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