Mutations of Glucose-6-Phosphate Dehydrogenase Durham, Santa-Maria and A+ Variants Are Associated with Loss Functional and Structural Stability of the Protein

Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in the world. More than 160 mutations causing the disease have been identified, but only 10% of these variants have been studied at biochemical and biophysical levels. In this study we report on the functional and str...

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Pubblicato in:Int J Mol Sci
Autori principali: Gómez-Manzo, Saúl, Marcial-Quino, Jaime, Vanoye-Carlo, America, Enríquez-Flores, Sergio, De la Mora-De la Mora, Ignacio, González-Valdez, Abigail, García-Torres, Itzhel, Martínez-Rosas, Víctor, Sierra-Palacios, Edgar, Lazcano-Pérez, Fernando, Rodríguez-Bustamante, Eduardo, Arreguin-Espinosa, Roberto
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691071/
https://ncbi.nlm.nih.gov/pubmed/26633385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226124
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