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DAG/PKCδ and IP3/Ca(2+)/CaMK IIβ Operate in Parallel to Each Other in PLCγ1-Driven Cell Proliferation and Migration of Human Gastric Adenocarcinoma Cells, through Akt/mTOR/S6 Pathway

Phosphoinositide specific phospholipase Cγ (PLCγ) activates diacylglycerol (DAG)/protein kinase C (PKC) and inositol 1,4,5-trisphosphate (IP3)/Ca(2+)/calmodulin-dependent protein kinase II (CaMK II) axes to regulate import events in some cancer cells, including gastric adenocarcinoma cells. However,...

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Dettagli Bibliografici
Pubblicato in:Int J Mol Sci
Autori principali: Dai, Lianzhi, Zhuang, Luhua, Zhang, Bingchang, Wang, Fen, Chen, Xiaolei, Xia, Chun, Zhang, Bing
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4691063/
https://ncbi.nlm.nih.gov/pubmed/26633375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms161226116
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