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HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts

HIV-1 Env mediates fusion of viral and target cell membranes, but it can also mediate fusion of infected (producer) and target cells, thus triggering the formation of multinucleated cells, so-called syncytia. Large, round, immobile syncytia are readily observable in cultures of HIV-1-infected T cell...

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Detalhes bibliográficos
Publicado no:Viruses
Main Authors: Symeonides, Menelaos, Murooka, Thomas T., Bellfy, Lauren N., Roy, Nathan H., Mempel, Thorsten R., Thali, Markus
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690882/
https://ncbi.nlm.nih.gov/pubmed/26703714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7122959
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