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Fluorescent Protein-Tagged Sindbis Virus E2 Glycoprotein Allows Single Particle Analysis of Virus Budding from Live Cells

Sindbis virus (SINV) is an enveloped, mosquito-borne alphavirus. Here we generated and characterized a fluorescent protein-tagged (FP-tagged) SINV and found that the presence of the FP-tag (mCherry) affected glycoprotein transport to the plasma membrane whereas the specific infectivity of the virus...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Jose, Joyce, Tang, Jinghua, Taylor, Aaron B., Baker, Timothy S., Kuhn, Richard J.
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690852/
https://ncbi.nlm.nih.gov/pubmed/26633461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7122926
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