Comparative pharmacokinetics and pharmacodynamics of a PEGylated recombinant human growth hormone and daily recombinant human growth hormone in growth hormone-deficient children

OBJECTIVE: Recombinant human growth hormone (rhGH) replacement therapy in children generally requires daily subcutaneous (sc) injections, which may be inconvenient for patients. Jintrolong(®) is a PEGylated rhGH with the purpose of weekly sc injections. The aim of the current study was to examine th...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Drug Des Devel Ther
Main Authors: Hou, Ling, Chen, Zhi-hang, Liu, Dong, Cheng, Yuan-guo, Luo, Xiao-ping
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2015
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690642/
https://ncbi.nlm.nih.gov/pubmed/26719670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S93183
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