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Effects of Incorporating Carboxymethyl Chitosan into PMMA Bone Cement Containing Methotrexate

Treatment of bone metastases usually includes surgical resection with local filling of methotrexate (MTX) in polymethyl methacrylate (PMMA) cement. We investigated whether incorporating carboxymethyl chitosan (CMCS) in MTX-PMMA cement might overcome disadvantages associated with MTX. To determine th...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Liu, Bo-Ming, Li, Ming, Yin, Bao-Sheng, Zou, Ji-Yang, Zhang, Wei-Guo, Wang, Shou-Yu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690603/
https://ncbi.nlm.nih.gov/pubmed/26657526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144407
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