Osmium-Based Pyrimidine Contrast Tags for Enhanced Nanopore-Based DNA Base Discrimination

Nanopores are a promising platform in next generation DNA sequencing. In this platform, an individual DNA strand is threaded into nanopore using an electric field, and enzyme-based ratcheting is used to move the strand through the detector. During this process the residual ion current through the po...

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Udgivet i:PLoS One
Main Authors: Henley, Robert Y., Vazquez-Pagan, Ana G., Johnson, Michael, Kanavarioti, Anastassia, Wanunu, Meni
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690601/
https://ncbi.nlm.nih.gov/pubmed/26657869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0142155
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