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Induction of human pancreatic beta cell replication by inhibitors of dual specificity tyrosine regulated kinase

Types 1 and 2 diabetes affect some 380 million people worldwide. Both result ultimately from a deficiency of functional pancreatic insulin-producing beta cells. Beta cells proliferate in humans during a brief temporal window beginning around the time of birth, with peak beta cell labeling indices ac...

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Detalhes bibliográficos
Publicado no:Nat Med
Main Authors: Wang, Peng, Alvarez-Perez, Juan-Carlos, Felsenfeld, Dan P., Liu, Hongtao, Sivendran, Sharmila, Bender, Aaron, Kumar, Anil, Sanchez, Roberto, Scott, Donald K., Garcia-Ocaña, Adolfo, Stewart, Andrew F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690535/
https://ncbi.nlm.nih.gov/pubmed/25751815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3820
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