Interferon-stimulated genes—essential antiviral effectors implicated in resistance to Theiler’s virus-induced demyelinating disease

BACKGROUND: Experimental infection of mice with Theiler’s murine encephalomyelitis virus (TMEV) is used as an animal model of human multiple sclerosis. TMEV persists in susceptible mouse strains and causes a biphasic disease consisting of acute polioencephalomyelitis and chronic demyelinating leukom...

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Publicado en:J Neuroinflammation
Autores principales: Li, Lin, Ulrich, Reiner, Baumgärtner, Wolfgang, Gerhauser, Ingo
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4690264/
https://ncbi.nlm.nih.gov/pubmed/26703877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0462-x
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