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Proper activation of MafA is required for optimal differentiation and maturation of pancreatic β-cells
A key therapeutic approach for the treatment of Type 1 diabetes (T1D) is transplantation of functional islet β-cells. Despite recent advances in generating stem cell-derived glucose-responsive insulin(+) cells, their further maturation to fully functional adult β-cells still remains a daunting task....
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| Gepubliceerd in: | Best Pract Res Clin Endocrinol Metab |
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| Hoofdauteurs: | , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2015
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4690007/ https://ncbi.nlm.nih.gov/pubmed/26696512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.beem.2015.09.006 |
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