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Increased lanosterol turnover: a metabolic burden for daunorubicin-resistant leukemia cells
The cholesterol metabolism is essential for cancer cell proliferation. We found the expression of genes involved in the cholesterol biosynthesis pathway up-regulated in the daunorubicin-resistant leukemia cell line CEM/R2, which is a daughter cell line to the leukemia cell line CCRF-CEM (CEM). Cellu...
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Publicado no: | Med Oncol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer US
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4689760/ https://ncbi.nlm.nih.gov/pubmed/26698156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12032-015-0717-5 |
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