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UPLC-MRM Mass Spectrometry Method for Measurement of the Coagulation Inhibitors Dabigatran and Rivaroxaban in Human Plasma and Its Comparison with Functional Assays

INTRODUCTION: The fast, precise, and accurate measurement of the new generation of oral anticoagulants such as dabigatran and rivaroxaban in patients’ plasma my provide important information in different clinical circumstances such as in the case of suspicion of overdose, when patients switch from e...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Kuhn, Joachim, Gripp, Tatjana, Flieder, Tobias, Dittrich, Marcus, Hendig, Doris, Busse, Jessica, Knabbe, Cornelius, Birschmann, Ingvild
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689546/
https://ncbi.nlm.nih.gov/pubmed/26699714
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145478
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